Translation of Wobble hypothesis in English

Wobble hypothesis Translation

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Wobble hypothesis in English
A wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules. The four main wobble base pairs are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A), and hypoxanthine-cytosine (I-C). In order to maintain consistency of nucleic acid nomenclature, "I" is used for hypoxanthine because hypoxanthine is the nucleobase of inosine; nomenclature otherwise follows the names of nucleobases and their corresponding nucleosides (e.g., "G" for both guanine and guanosine). The thermodynamic stability of a wobble base pair is comparable to that of a Watson-Crick base pair. Wobble base pairs are fundamental in RNA secondary structure and are critical for the proper translation of the genetic code.

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More: English to English translation of Wobble hypothesis
Hypothesis to explain how one tRNA can recognize two codons. The third base in the anticodon can pair with more than one bases. This is due to the degeneracy of the genetic code which results in more than one triplet codes for some amino acids.

Copyright: Dictionary source: Common Terms in Evolutionary Biology and Genetics
More: English to English translation of Wobble hypothesis